A multimodal biomarker for concussion identification, prognosis and management.

Jacquin A, Kanakia S, Oberly D, Prichep L. 

Computer in Biology and Medicine. 2018; 102:95-103.

Traumatic brain injury (TBI) accounts for over 1.5 million emer-gency department (ED) visits annually within the United States and the vast majority of these visits are for mild injury (mTBI/concussion) [1]. In addition, the Center for Disease Control (CDC) estimates that 1.6 to 3.8 million concussions occur in sports and recreational activities an-nually. These figures are likely to significantly underestimate the TBI burden since many patients with mild head injuries do not seek medical care [2]. Results from a recent (2017) large scale (N = 14,765 stu-dents), voluntary Youth Risk Behavior Survey (YRBS) performed by the CDC report that approximately 15.1% of US high school students (ap-proximately 2.5 million) reported having had at least one concussion in the past 12 months, 6% reported having two or more, and this number rises to as high as 30.3% in those who play on three or more sports teams per year. Download the PDF